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Stanford V (usually spoken as ''Stanford Five'') is a chemotherapy regimen (with or without accompanying Radiation therapy) intended as a first line treatment for Hodgkin's lymphoma. The regimen was developed in 1988, with the objective of maintaining a high remission rate while reducing the incidence of acute and long term toxicity, pulmonary damage, and sterility observed in alternative treatment regimens such as ABVD. The chemical agents used are: * A mustard derivative such as Cyclophosphamide, Mechlorethamine or Ifosfamide * Doxorubicin, an anti-tumor antibiotic * Vinblastine, an alkaloid cell toxin * Vincristine, another alkaloid cell toxin * Bleomycin, another anti-tumor antibiotic * Etoposide, a DNA toxin * Prednisone, a corticosteroid Drug Regimen〔(【引用サイトリンク】url=http://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=12424 )〕 The chemotherapy part of Stanford V treatment can last anywhere from 8 to 12 weeks, depending on the staging of the disease. In many cases, this is followed by radiation therapy for anywhere from 2 to 6 weeks to the affected areas of the body. Stanford V is a more rigorously administered form of chemotherapy, with treatments roughly twice as fast as those of other Hodgkin's lymphoma treatments. However, in a randomized controlled study, Stanford V was inferior to ABVD. This study has been criticized for not adhering to the proper Stanford V protocol. Specifically, the radiation therapy component following chemotherapy was not properly administered in the Italian study. A retrospective study from the Memorial Sloan-Kettering Cancer Center displayed results similar to the Stanford Cancer Center's own experience. The study concluded that, "Stanford V with appropriate radiotherapy is a highly effective regimen for locally extensive and advanced HL." ==External links== * (Lymphoma Information Network ) * PMID 11821442 * (Includes table for schedule ) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Stanford V」の詳細全文を読む スポンサード リンク
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